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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Immunol Cell Biol. 2011 Apr 26;90(1):124–129. doi: 10.1038/icb.2011.29

Figure 2.

Figure 2

SOCS3 regulates responses to IL-1β in vivo. (A) SOCS3−/Δ vav mice are hypersensitive to IL-1β, resulting from loss of regulation of IL-6. n=4–5 per group. (B) SOCS3 regulates cytokine production independently of IL-6 after challenge with IL-1β. Cytokine production was analysed in the serum of mice injected with IL-1β.