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IL-1β induces loss of cells in the bone marrow (A) and apoptosis of leukocytes in the thymus (B) of SOCS3−/Δ vav mice but not IL-6−/−/SOCS3−/Δ vav mice. Tissues were stained with haematoxylin and eosin. (C) Flow cytometric analysis of haemopoietic cells in the bone marrow from IL-1β-injected wild-type and SOCS3−/Δ vav mice, 36 h after injection.
