Fig. 4.
KSHV infection of endothelial cells alters cytokine production and secretion. (A) Depicted is the fold change of IL6 and IL8 transcripts in KSHV-infected TIME cells compared to UV-irradiated virus treated cells at 48 h postinfection as determined by real-time RT-PCR (N = 3). All values were normalized to GAPDH expression and error bars represent the standard error of the mean. (B) A cytokine antibody array was used to monitor secreted cytokines from KSHV-infected and mock-infected primary human DMVECs by probing the antibody-spotted membrane with diluted supernatants from 48 to 96 h postinfection.