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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: FEMS Immunol Med Microbiol. 2011 Jun 16;62(3):283–294. doi: 10.1111/j.1574-695X.2011.00816.x

Figure 5. Effects of Fluoxetine and Desipramine on the production of cytokines and chemokines by LPS-stimulated DC.

Figure 5

DCs were stimulated with or without LPS (1μg/mL) in the presence or absence of Fluoxetine or Desipramine (1 μM) for 24 hours. The concentrations of TNF-α, IL-1β, IL-12, RANTES, MIP-1α and IL-10 in the culture supernatant were measured using ELISA. Results are expressed as the mean ± SD of cytokines/chemokines concentrations (pg/mL) of triplicate cultures. One representative result from three different experiments is shown. *, significantly lower than no drug treatment by Student’s t test (P < 0.01).