Skip to main content
. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Bioorg Med Chem. 2010 Dec 15;19(3):1298–1305. doi: 10.1016/j.bmc.2010.12.003

Scheme 2.

Scheme 2

Reagents and conditions: (a) DMAP, pivaloyl anhydride, refluxing 6 h; (b) H2 50 Psi/5%Pd-C, 2-methoxy-ethanol, RT, 3 h or Fe-AcOH, EtOH refluxing 2 h; (c) 1) AcOH, 4-formyl-benzoic acid methyl ester, RT, overnight; 2) borane-tert-butylamine complex.