Fig. 5.
In vivo regulation of the gluconeogenic program by bcatenin. (A) Relative expression of G6PC and PCK1 after in vivo deletion of hepatic β-catenin. n = 3; triplicate determinations from three animals in each group. (B) Expression of G6PC and PCK1 3 days after delivery of either a control or a β-catenin–expressing adenovirus. n = 4; triplicate determinations from four mice per group. (C) ChIP assay demonstrating increased in vivo β-catenin binding to the G6PC and PCK1 promoter after mice were fasted for 18 hours. n = 6 mice per condition. *P < 0.05, Student's t test.