Table 3.
Concordance between the two commercial IGRAs stratified by study visit
| Visit no. (study day) | No. of subjects per visit | No. (%) of positive QFT results | No. (%) of positive T-SPOT results | No. (%) of discordant IGRA results | Agreement between QFT and T-SPOT results |
|
|---|---|---|---|---|---|---|
| Raw (%) | Kappa (P) | |||||
| 1 (0) | 35 | 12 (34.3) | 10 (28.6) | 8 (22.9) | 77.1 | 0.47 (0.005) |
| 2 (+7) | 35 | 12 (34.3) | 10 (28.6) | 6 (17.1) | 82.9 | 0.60 (<0.001) |
| 3 (+14) | 30 | 7 (23.3) | 7 (23.3) | 2 (6.7) | 93.3 | 0.81 (<0.001) |
| 4 (+21) | 31 | 5 (16.1) | 5 (16.1) | 2 (6.5) | 93.5 | 0.76 (<0.001) |
| 5 (+28) | 27 | 4 (14.8) | 4 (14.8) | 2 (7.4) | 92.6 | 0.71 (<0.001) |
| Total | 158 | 40 (25.3) | 36 (22.8) | 20 (12.7) | 87.3 | 0.65 (<0.001) |