Skip to main content
. 2011 Jul;18(7):1167–1175. doi: 10.1128/CVI.00035-11

Fig. 2.

Fig. 2.

HAI titers against A/Solomon Islands, A/Wisconsin, and B/Malaysia viruses following vaccination of naïve ferrets with NE-adjuvanted Fluzone. Ferrets received 500 μl vaccine containing HA doses ranging from 7.5 to 36 μg. Sera were collected on day 27 following a single intranasal vaccination on day 1. The numbers above the bars represent the seroconversion rates. There was a statistically significant difference (*) between nasal NE-adjuvanted vaccine and nasal nonadjuvanted vaccine for the A/Solomon Islands and B/Malaysia strains with all the doses administered (P ≤ 0.06). For the A/Wisconsin strain, a statistically significant difference was observed only between the 36-μg adjuvanted and nonadjuvanted Fluzone vaccines (P = 0.004). There was no significant difference between the 7.5-μg (P = 0.6) or 22.5-μg (P = 0.4) adjuvanted vaccine and the 36-μg nonadjuvanted vaccine.