Table 3.
In vivo mouse trial using IgY to H5N1 and protection based on weight gain and mortalitya
| Group | Weight gain or loss (%) | Day measured | Mortality |
|---|---|---|---|
| PBS control | −30.1 | 7 | Euthanized on day 7 |
| −13.8 | 7 | Died on day 10 | |
| −22.3 | 7 | Euthanized on day 7 | |
| −11.1 | 3 | Died on day 7 | |
| −6.7 | 3 | Died on day 6 | |
| H5N1 IgY | +0.1 | 7 | Survived to day 16 |
| +3.6 | 7 | Survived to day 16 | |
| +2.5 | 7 | Survived to day 16 | |
| +6.9 | 7 | Survived to day 16 | |
| +2.5 | 7 | Survived to day 16 |
a
Results from individual BALB/c mice given either PBS or IgY to H5N1 and then challenged 1 h later.