Fig. 1.

Percentages of B cells from PBMCs isolated from control noninfected calves (⧫) and calves infected with Mycobacterium avium subsp. paratuberculosis by the following methods: oral (▪), intraperitoneal (▴), oral with dexamethasone administration (○), and oral with mucosal scrapings from a cow with clinical disease (*). Data are for a 12-month study with nonstimulated PBMCs (A) and PBMCs stimulated with a whole-cell sonicate of Mycobacterium avium subsp. paratuberculosis (MPS) (B). Data are expressed as means ± SEM. Significant differences between control and infection groups for given time points are represented by asterisks (*, P < 0.01; **, P < 0.05).