Fig. 5.

Percentages of CD25⁺ B cells from PBMCs isolated from control noninfected calves and calves infected with Mycobacterium avium subsp. paratuberculosis by the following methods: oral, intraperitoneal, oral with dexamethasone administration, and oral with mucosal scrapings from a cow with clinical disease. Data are for a 12-month study with nonstimulated PBMCs (A) and PBMCs stimulated with MPS (B). Data are expressed as means ± SEM. Significant differences between the control and infection groups for given time points are represented by asterisks (*, P < 0.01; **, P < 0.05).