Table 2.
Assignment of immunotype to 498 N. meningitidis serogroup A strainsa
| Classification method (reference) | No. of N. meningitidis serogroup A strains by type |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Invasive |
Carrier |
||||||||||||
| Origin of isolate | L(3,7)9 | L10 | L11 | L10,11 | Other | ND | Origin of isolate | L(3,7)9 | L10 | L11 or L10,11 | Other | ND | |
| SDS-PAGE against mouse MAbs (16) | China | 2 | 7 | 6 | 0 | 0 | 1 | ||||||
| United States | 0 | 1 | 1 | 1 | 0 | 1 | |||||||
| Others | 4 | 2 | 1 | 0 | 1 | ||||||||
| Western blotting with SDS-PAGE against both mouse monoclonal antibodies and reference hyperimmune rabbit sera (25) | Sudan | 1 | 18 | 2 | 0 | 4 | 0 | ||||||
| Sweden | 9 | 5 | 9 | 0 | 2 | 0 | |||||||
| Western blotting with SDS-PAGE against both mouse monoclonal antibodies and reference hyperimmune rabbit sera (1) | Various | 154 | 122 | 49 | 0 | 9 | 21 | ||||||
| Solid-phase radioimmunoassay inhibition serotyping with rabbit polyclonal antisera (34) | Germany | 0 | 9 | 1 | 0 | 0 | 0 | ||||||
| Africa | 7 | 5 | 0 | 0 | 0 | 0 | |||||||
| Finland | 0 | 0 | 4 | 0 | 1 | 1 | |||||||
| Brazil | 0 | 6 | 0 | 0 | 0 | 0 | |||||||
| North America | 2 | 24 | 2 | 1 | 0 | 2 | North America | 1 | 2 | 10 | 0 | 2 | |
| Ouchterlony immunodiffusion with rabbit polyclonal antisera and/or whole-cell ELISA with a panel of 14 MAbs (24, 26) | Various | 5 | 11 | 1 | 9 | 0 | Various | 0 | 4 | 1 | 2 | 0 | |
| Total | 179 | 199 | 75 | 2 | 17 | 26 | 1 | 6 | 11 | 2 | 2 | ||
| Percentage of total | 35.9 | 40.0 | 15.1 | 0.4 | 3.4 | 5.2 | 4.5 | 27.3 | 50.0 | 9.1 | 9.1 | ||
a
MAbs, monoclonal antibodies; ND, not determined.