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Characteristics of GXM MAbs
| MAb | GXM used for immunization | Isotype | Serotype reactivity | Reference(s) |
|---|---|---|---|---|
| 3C2 | Serotype C | IgG1 | A, B, C, and D | 3, 19, 25 |
| 471 | Serotype A | IgG1 | A, B, C, and D | 3, 19, 25 |
| 339 | Serotype B | IgG1 | A, B, and D | 3, 19, 25 |
| 1255 | Serotype A | IgG1 | A, B, and D | 3, 12, 19 |
| F12D2 | De-O-Aa | IgG1b | A, B, C, and D | 7 |
De-O-A, de-O-acetylated GXM of serotype A.
The F12D2 MAb used in this study is a subclass switch variant (IgG3→IgG1) of MAb F12D2 described in reference 7.
