Table 3.
Sensitivities of four commercially available immunoassays for detection of GXM of different serotypes
| Immunoassay | Assay formatb | Minimum concn of GXM (ng/ml) producing a positive resulta |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| A |
B |
C |
D |
|||||||
| CN6 | MU-1 | 184 | 409 | 34 | 298 | 24066 | 127 | M0024 | ||
| Immuno-Mycologics | LA | 24 | 32 | 27 | 68 | 432 | 260 | 460 | 62 | 63 |
| Meridian CALAS | LA | 18 | 20 | 52 | 22 | >2,000 | 470 | 360 | 44 | 65 |
| Inverness | LA | 38 | NTc | 64 | NT | >2,000 | 940 | >2,000 | 50 | NT |
| Meridian Premier | ELISA | 35 | 22 | 25 | 21 | >2,000 | >2,000 | >2,000 | 900 | 630 |
a
Results are shown for GXM isolated from different strains of each serotype. >2,000, GXM of some strains of serotype C produced negative results at all concentrations up to 2,000 ng/ml.
b
LA, latex agglutination; ELISA, antigen capture sandwich enzyme-linked immunosorbent assay.
c
NT, not tested.