Table 3.
Comparison of serum cytokine concentrations in HIV− and chronically HIV+ subjects for Linco analytes with a majority of detectable results
| Cytokine | Median concn (pg/ml)a |
|
|---|---|---|
| HIV− | HIV+ | |
| IL-2 | 1.9 (0.5–4.2) | 0.6 (<0.1–1.8) |
| IL-5 | 0.3 (<0.1–0.7) | 0.2 (<0.1–0.8) |
| IL-6 | 4.7 (2.3–10.3) | 5.9 (1.9–15.0) |
| IL-7 | 8.0 (4.7–12.3) | 7.8 (4.1–11.5) |
| IL-8 | 9.6 (4.7–30.7) | 10.4 (5.1–34.0) |
| IL-10 | 8.8 (6.1–22.0) | 9.5 (6.2–13.4) |
| IL-13 | 4.0 (0.2–18.3) | 1.4 (0.2–54.9) |
| GM-CSF | 1.4 (<0.1–4.4) | <0.1 (<0.1–1.1) |
| TNF-α | 5.9 (4.1–8.9) | 9.0 (6.8–14.1) |
a
Unadjusted median cytokine concentrations and interquartile ranges (25th to 75th percentiles, in parentheses). Values shown in boldface indicate P values of <0.05 in adjusted means between HIV− and HIV+ subjects, taking lab and lot differences into account.