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Box plot showing the serum PRN-IgG measured by the in-house ELISA of the sera before and after the administration of the fifth dose. A single measurement using serial 2-fold dilutions of serum was examined; n=80 and 75 in pre- and postvaccination groups, respectively. The scatter plot shows the PRN-IgG distribution of the 75 paired pre- and postvaccination sera.
