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. 2011 Aug;18(8):1306–1316. doi: 10.1128/CVI.05118-11

Fig. 1.

Fig. 1.

Decreased numbers and frequency of memory B cells in sarcoidosis patients. (A) Representative example of CD19 and CD27 expression on PBMC. The frequencies of naïve and memory B cells in sarcoidosis patients and healthy controls are compared. Results are given as percentages (means ± standard deviations). Plasmablasts (CD19+/− CD27++) are shown within dotted circles. (B through G) Frequencies of total (CD19+) (B), naïve (CD19+ CD27−) (D), or memory (CD19+ CD27+) (F) B cells and absolute numbers of total (C), naïve (E), and memory (G) B cells were determined by dual-platform FC of PBMC from patients with sarcoidosis and healthy controls. (H) Analysis of CD19 and CD5 expression in blood B cells purified from sarcoidosis patients and healthy controls by magnetic-activated cell sorting. Horizontal lines indicate median percentages and median absolute numbers of the different populations.