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. 2011 Aug;18(8):1306–1316. doi: 10.1128/CVI.05118-11

Fig. 4.

Fig. 4.

Expression levels of costimulatory (CD19, CD21, and CD45) and coinhibitory (CD32, CD35, CD85J, and CD152) receptors in sarcoid B cells. CD19+ cells, purified from PBMC of sarcoid patients and healthy controls by magnetic-activated cell sorting, were either left unstimulated or stimulated for 24 h with CD40L, CpG-ODN, IL-2, IL-10, and IL-15. The cells were then analyzed by FC for levels of expression of CD19 (A), CD21 (B), CD45 (C), CD32 (D), CD35 (E), CD85J (F), and CD152 (G). Horizontal lines indicate the median MFI for each of the indicated markers. Representative histograms are shown at the bottoms of all panels. Thin lines, isotype control; thick black lines, sarcoidosis cells; thick gray lines, control cells.