Fig. 3.

Effects of prodigiosin and cycloprodigiosin on microorganisms and cancer cell lines. Comparison of the antimicrobial activities of prodigiosin and cycloprodigiosin purified from Zooshikella rubidus S1-1 (A). DMSO was used as a vehicle solvent and negative control. Human melanoma cancer cells were treated with prodigiosin (B) and cycloprodigiosin (C) at various concentrations or with vehicle solvent (0.1% DMSO). All assays were performed in triplicate, and error bars represent standard deviations from the means.