Table 3.

Biochemically characterized QQ hydrolases in microorganisms and metagenomes

Protein	Source or strain	Protein family	Conserved motif	Reference
AiiA	Bacillus sp. strain 240B1	Metallo-β-lactamase superfamily	HxHx∼DH	12
AiiB/AttM	Agrobacterium tumefaciens strain C58	Metallo-β-lactamase superfamily	HxHx∼DH	5
AhlD	Arthrobacter sp. strain IBN110	Metallo-β-lactamase superfamily	HxHx∼DH	32
AhlK	Klebsiella pneumoniae	Metallo-β-lactamase superfamily	HxHx∼DH	32
QlcA	Soil metagenome	Metallo-β-lactamase superfamily	HxHx∼DH	36
QsdR1	Rhizobium sp. strain NGR234	Metallo-β-lactamase superfamily	HxHx∼DH	This study
AidH	Ochrobactrum anthropi ATCC 49188	α/β-Hydrolase fold family	GX-Nuc-XG	28
AiiM	Microbacterium testeceum StLB037	α/β-Hydrolase fold family	NDa	54
BpiB04	Soil metagenome	Glycosyl hydrolase family	ND	39
BpiB07	Soil metagenome	Dienelactone hydrolase family	ND	39
DlhR	Rhizobium sp. strain NGR234	Dienelactone hydrolase family	GSD(L)	This study
BpiB01	Soil metagenome	Hypothetical protein	ND	39
BpiB05	Soil metagenome	Hypothetical protein	ND	3
QsdA	Rhodococcus erythropolis W2	PTE superfamily	PTE domain	51

^aND, none detected.