Table 2.
Distribution of study subject infection status among oyster treatment groups
| Phase | Treatment conditions | No. of subjects infected/total (%) postchallenge with: |
P valueb | |
|---|---|---|---|---|
| HPP-treated oysters | Untreated oystersa | |||
| 1 | 400 MPa, 25°C, 5 min | 3/5 (60) | 7/15 (47) | 1.0000 |
| 2 | 600 MPa, 6°C, 5 min | 0/10 (0) | 7/15 (47) | 0.0202 |
| 3 | 400 MPa, 6°C, 5 min | 3/14 (21) | 7/15 (47) | 0.2451 |
a
The control group represented the combined number of controls over phase 1 through phase 3 (n = 15) because each control received untreated HuNoV-seeded raw oysters with the same amount of HuNoV inoculum.
b
Fisher's exact two-sided test compared each treatment group to all of the controls (i.e., the total number of subjects challenged with non-HPP treated oysters).