Arrangement and sequence identity of the Wood-Ljungdahl gene cluster in C. autoethanogenum (CAU), C. ljungdahlii (CLJ), and C. ragsdalei (CRA). The graph at the top shows the percentages of identity between all 3 sequences. Variations are marked in black or as gaps in the gray sequence bar above the annotations. Alignments were created using Geneious (Biomatters Ltd., Auckland, New Zealand). acs, genes for the CODH/ACS complex; acsA, CODH subunit gene; acsB, ACS subunit gene; acsC, corrinoid iron-sulfur protein large subunit gene; acsD, corrinoid iron-sulfur protein small subunit gene; acsE, methyltransferase subunit gene; cooC, gene for CODH accessory protein; fchA, formimido-tetrahydrofolate cyclodeaminase gene; fdx, ferredoxin gene; fhs, formyl-tetrahydrofolate synthase gene; folD, bifunctional methylene-tetrahydrofolate dehydrogenase/formyl-tetrahydrofolate cyclohydrolase gene; gcvH, gene for glycine cleavage system H protein; lpdA, gene for dihydrolipoamide dehydrogenase; metF, methylene-tetrahydrofolate reductase gene; T, predicted terminator; X, gene for conserved zinc finger protein of unknown function.