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pdeB mutant cells are unable to complete the mouse-tick-mouse infection cycle
| Strain | No. of spirochetes/mouse | % of mice infected | % of ticks infected | Mean no. of spirochetes/nymph ± SD | No. of nymphs per mouse | No. of mice infected/total |
|---|---|---|---|---|---|---|
| Wild type | 5 × 104 | 100 | 50 | 20,900 ± 11,172 | 30 | 4/4 |
| pdeB mutant | 5 × 105 | 100 | 50 | 4,466 ± 702 | 30 | 0/4 |
| Complemented pdeB+ | 5 × 104 | 100 | 60 | 15,666 ± 757 | 30 | 2/4 |
