Table 1.
Codon usage is compared for BoNT/A Hc gene fragments
| Amino acid | Codon | No. of times codon occursa |
||
|---|---|---|---|---|
| WT | Y | SF | ||
| Ala | GCG | 0 | 1 | 0 |
| Ala | GCA | 5 | 0 | 3 |
| Ala | GCT | 5 | 9 | 3 |
| Ala | GCC | 0 | 0 | 4 |
| Cys | TGT | 2 | 1 | 1 |
| Cys | TGC | 2 | 3 | 3 |
| Asp | GAT | 22 | 5 | 7 |
| Asp | GAC | 2 | 19 | 17 |
| Glu | GAG | 1 | 1 | 12 |
| Glu | GAA | 17 | 17 | 6 |
| Phe | TTT | 17 | 0 | 6 |
| Phe | TTC | 0 | 17 | 11 |
| Gly | GGG | 3 | 0 | 0 |
| Gly | GGA | 8 | 0 | 4 |
| Gly | GGT | 10 | 22 | 11 |
| Gly | GGC | 2 | 1 | 8 |
| His | CAT | 4 | 0 | 1 |
| His | CAC | 0 | 4 | 3 |
| Ile | ATA | 24 | 0 | 6 |
| Ile | ATT | 22 | 0 | 15 |
| Ile | ATC | 3 | 49 | 28 |
| Lys | AAG | 4 | 8 | 23 |
| Lys | AAA | 29 | 25 | 10 |
| Leu | TTG | 3 | 1 | 5 |
| Leu | TTA | 23 | 0 | 0 |
| Leu | CTG | 1 | 33 | 17 |
| Leu | CTA | 4 | 0 | 0 |
| Leu | CTT | 3 | 0 | 3 |
| Leu | CTC | 0 | 0 | 9 |
| Met | ATG | 9 | 9 | 9 |
| Asn | AAT | 53 | 25 | 19 |
| Asn | AAC | 4 | 32 | 38 |
| Pro | CCG | 0 | 9 | 0 |
| Pro | CCA | 5 | 0 | 3 |
| Pro | CCT | 4 | 0 | 2 |
| Pro | CCC | 0 | 0 | 4 |
| Gln | CAG | 4 | 15 | 10 |
| Gln | CAA | 11 | 0 | 5 |
| Arg | AGG | 5 | 0 | 5 |
| Arg | AGA | 14 | 0 | 2 |
| Arg | CGG | 0 | 0 | 0 |
| Arg | CGA | 0 | 0 | 0 |
| Arg | CGT | 1 | 13 | 6 |
| Arg | CGC | 0 | 7 | 7 |
| Ser | AGT | 15 | 0 | 3 |
| Ser | AGC | 2 | 0 | 9 |
| Ser | TCG | 0 | 0 | 0 |
| Ser | TCA | 11 | 0 | 5 |
| Ser | TCT | 6 | 20 | 6 |
| Ser | TCC | 0 | 14 | 11 |
| Thr | ACG | 0 | 0 | 1 |
| Thr | ACA | 6 | 0 | 4 |
| Thr | ACT | 10 | 7 | 4 |
| Thr | ACC | 0 | 9 | 7 |
| Val | GTG | 0 | 0 | 12 |
| Val | GTA | 19 | 9 | 3 |
| Val | GTT | 3 | 13 | 2 |
| Val | GTC | 1 | 1 | 6 |
| Trp | TGG | 9 | 9 | 9 |
| Tyr | TAT | 26 | 0 | 5 |
| Tyr | TAC | 2 | 28 | 23 |
| End | TGA | 0 | 0 | 0 |
| End | TAG | 0 | 0 | 0 |
| End | TAA | 0 | 0 | 0 |