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. 2011 Aug;31(15):3146–3157. doi: 10.1128/MCB.01187-10

Fig. 1.

Fig. 1.

Localization of HspB1 in AD and transgenic mouse models of AD. Immunohistochemistry of HspB1 (A, C, and E) and HspB5 (B, D, and F) in AD hippocampal sections (A and B), cortical sections of 12-month-old Tg2576 mice (C and D), and 18-month-old APPswePS1dE9 mice (E and F) to show colocalization with plaques. Colocalization of Aβ (green) and HspB1 or HspB5 (red) with the nuclear stain DAPI (4′,6-diamidino-2-phenylindole; blue). The arrows in panels A and B indicate the reactive astrocytes. The asterisks in panel A indicate the penumbral staining of HspB1 (no penumbral staining was observed for HspB5).