Table 2.

Positive compounds in the screen of the Prestwick chemical library

Compound	Function	Contraction frequency (10−6)
		Round 1	Round 2
DMSO	Organic solvent (control)	3.0	8.9
Acacetin	Anticancer drug, TOP1 inhibitor	80	40
Acyclovir	Inhibits viral DNA polymerase	20	136
Amikacin	Aminoglycoside antibiotic	13	87
Amphotericin B	Polyene antifungal drug	53
Amprolium	Antiprotozoal agent	33	76
Antipyrine	Analgesic and antipyretic agent	27
Betulinic acid	Anticancer agent	67	75
Butirosin	Aminoglycoside antibiotic	20	52
Chinchonine	Antimalaria agent	27
Hydroflumethiazide	Thiazide diuretic	60	78
Mefloquine	Antimalarial agent	33
Metformin	Antimalarial agent	27
Oleandomycin	Macrolide antibiotic	20
Syrosingopine	Antipsychotic and antihypertensive	53
Thiamine	Vitamin B1	67	143
Trihexyphidyl	Muscarinic antagonist	13
Vidarabine	Antiviral drug	47	98
Vitexin	Flavonoid with antioxidant activity	27	38