Table 2.
Biological activity of BMS-346a
Replicon | EC50 (μM) | CC50 (μM) |
---|---|---|
WT HCV | 0.000086 | >10 |
Y93H | 4 | >10 |
BVDV | >10 | >10 |
EC50s were derived from this single experiment. On multiple test occasions, the average EC50s and standard deviations of BMS-346 were as follows: wild type (WT), 0.000052 ± 0.0000076 μM; Y93H, 3.5 ± 3.1 μM.