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Determination of MTD of C12K-2α8 in ICR mice
| Dose (mg/kg) | Administration route | Observation | Survivala | MTD (mg/kg) |
|---|---|---|---|---|
| 5 | i.v. | No signs of toxicity | 7/7 | 5 |
| 12.5 | i.v. | Brief malaise signs | 7/7 | 5 |
| 12.5 | i.p. | No signs of toxicity | 7/7 | >25 |
| 25 | i.p. | No signs of toxicity | 7/7 | >25 |
No. of surviving mice/no. tested.
