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. 2011 Aug;55(8):3684–3690. doi: 10.1128/AAC.01729-10

Table 1.

Cumulative percentages of inhibition results at each linezolid MIC with testing of six different groups of Gram-positive cocci isolated from all U.S. Census regions (LEADER Program, 2009; 6,414 strains)

Organism group (no. tested) Cumulative % inhibited at linezolid MIC (μg/ml) of:
≤0.12 0.25 0.5 1 2 4 8 >8
Viridans group streptococci (264) 1.1 2.7 34.5 97.7 100.0
S. pneumoniae (659) 0.6 3.8 43.4 96.5 100.0
Beta-hemolytic streptococci (401) 0.5 0.5 11.2 99.5 100.0
CoNS (816) 0.1 1.4 37.1 94.4 98.3 98.5 98.9 100.0a
Enterococci (1,017) 0.0 0.1 4.0 53.4 98.9 99.2 99.6b 100.0b
S. aureus (3,257) 0.1 0.2 0.9 41.5 99.8 99.9 >99.9c 100.0c
a

Nine strains from eight states (all S. epidermidis, and eight strains were methicillin resistant).

b

Eight strains from 5 states, all E. faecium (four strains with MICs of 8 μg/ml and four strains with MICs of >8 μg/ml).

c

Five strains from 5 states (three strains with MICs of 8 μg/ml and two strains with MICs of >8 μg/ml); all were MRSA.