Time-kill curves for MX-2401 (A), vancomycin (B), and daptomycin (C) versus S. aureus (MRSA strain ATCC 19636) and of MX-2401 (D), vancomycin (E), and daptomycin (F) versus E. faecalis (strain ATCC 29212). MICs of MX-2401, vancomycin, and daptomycin against S. aureus were 0.25, 0.5, and 0.5 μg/ml, respectively; MICs against E. faecalis were 2, 1, and 2 μg/ml, respectively.