Table 2.
Comparison of total cost to result for 927 clinical bacterial isolatesa
Organism group | No. of isolates | Cost (AUD$) |
Cost savings per group (AUD$) | |
---|---|---|---|---|
Current method | Using MALDI-TOF MSb | |||
Anaerobes | 12 | 126.00 | 5.40 | 120.60 |
Enterobacteriaceae | 298 | 3,314.64 | 1,010.78c | 2,303.86 |
Gram-positive rods | 33 | 833.91 | 344.85d | 489.06 |
Gram-positive cocci | 429 | 3,714.21 | 527.56e | 3,186.65 |
Miscellaneous gram-negatives | 78 | 1,471.82 | 35.10 | 1,436.72 |
Non-fermentative gram-negative rods | 77 | 893.43 | 34.65 | 858.78 |
Total | 927 | 10,354.01 | 1,958.34 | 8,395.67 |
Includes reagent and labor costs based upon one identification attempt per isolate.
Only six isolates required crude extraction to provide an acceptable identification. This added an additional AUD$2.70 to the total cost of the MALDI-TOF identifications.
Includes the cost of conventional identification methods (including serological confirmation) for 28 isolates that could not be identified by MALDI-TOF MS.
Includes the cost for the identification of three isolates by 16S rRNA analysis.
Includes the cost for additional identification methods such as optochin susceptibility for 38 isolates.