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. 2011 Aug;31(16):3252–3266. doi: 10.1128/MCB.05251-11

Table 4.

EC50s obtained for wild-type and mutant IFN-α2 and IFN-β for antiproliferative activity of WISH cells and six breast cancer cell lines

Interferon EC50 (nM)a
WISH MDA-MB-231 MDA-MB-468 MCF7 T-47D BT-549 HS 578T
IFN-α2 3.6 0.29 0.69 0.73 0.4 4.2 12.9
IFN-β 0.057 0.014 0.035 0.044 0.02 0.04 0.017
YNS 0.023 0.0038 0.0048 0.015 0.038 0.0074 0.009
YNS-α8tail 0.012 0.0014 0.0031 0.014 0.0029 0.0082 0.004
a

EC50s were determined from dose-response curves, fitted to equation 2.