Fig. 7.

Aberrant Cdc25A expression correlates with human breast cancer metastasis. (A and B) The relative Cdc25A mRNA (A) and protein (B) levels in human invasive cells versus noninvasive cells were evaluated by qRT-PCR and Western blotting. The error bars indicate SD. (C) Representatives of the Cdc25A signal intensity stages. The samples were graded on a scale of 1 (lowest) to 5 (maximum staining) scores or stages according to the Cdc25A signal intensity in the patient breast cancer samples. (D and E) Distribution of the invasive breast cancer patient cases (D) and noninvasive breast cancer patient cases (E) among the different Cdc25A signal intensity stages.