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Nuclear localization of Ubc9 restores H3K9me3 levels in cells expressing progerin. (A) IF localization of HA-progerin and nuclear H3K9me3 in cells cotransfected with Ubc9. Scale bar, 20 μm. (B) Histograms showing H3K9me3 levels (bin size = 1) in HA-positive cells expressing engineered forms of Ubc9.
