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. 2011 Aug;31(16):3472–3484. doi: 10.1128/MCB.05587-11

Fig. 7.

Fig. 7.

Effects of zeburaline treatment on Dnmt protein levels, Dnmt1 activity, and CpG methylation. (A) Western blot analysis of Dnmt proteins in RL4 cells that were exposed to zebularine for 3 days (d3), 18 days (d18), or 28 days (d28). RL4 cells carrying an LCR–Pro–EGFP transgene cassette (No Rep-P) and RL4 cells carrying an LCR–Pro–EGFP–Rep-PAG2 transgene cassette (Rep-PAG2) were exposed to zebularine (Zeb). (B) Results of bisulfite sequencing of genomic DNA from RL4 cells exposed to zebularine. Me, methylated.