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Nucleotide sequence variations among the HPV 16 isolates. The E6, E7, L1, and LCR variants were identified in 52 samples from northeast China. The nucleotide positions of detected mutations are written vertically across the top and are indicated by the corresponding nucleotide letter. The absence of variations relative to the prototype is represented by dashes. The identification codes of the samples are indicated on the left. 16R, HPV 16 reference; Ep, European prototype; As, Asian.
