Table 3.

Accuracyindicators of HPV mRNA test in 723 women with abnormal cytology and HPV DNA positive test shown by cytological grade^a

Cytology	No. of women tested	No. of women with colposcopy follow-up	No. of CIN2+ women	Test positivityb		Sensitivityc		Specificityd		PPV		NPV
				%	95% CI	%	95% CI	%	95% CI	%	95% CI	%	95% CI
ASC-US	175	103	25	47	38–56	72	51–88	74	63–84	47	31–64	89	79–96
L-SIL	399	254	48	36	31–41	67	52–80	72	65–78	36	26–46	90	85–94
H-SIL+	149	132	101	70	62–77	70	60–79	42	25–61	80	70–88	30	17–46

^aAbbreviations are as defined in Table 1, footnote a.

^bTest positivity and its 95% CI are calculated based on the total number of tested women.

^cSensitivity and its 95% CI are calculated based on the number of CIN2+ women.

^dSpecificity and its 95% CI are calculated based on the number of CIN2− women, i.e., (the number of women withcolposcopy follow-up) − (the number of CIN2+ women).