Table 3.
Geometric mean MICs for fluconazole by species and fluconazole use
| Transplant type and Candida species (n) | Geometric mean MIC (μg/ml) |
P value | ||
|---|---|---|---|---|
| All isolates | Fluconazole prophylaxis | No fluconazole prophylaxis | ||
| All transplant types | ||||
| All species (383) | 1.746 | 7.207 | 1.238 | <0.001 |
| C. albicans (154) | 0.309 | 0.330 | 0.308 | 0.694 |
| C. glabrata (119) | 12.550 | 19.870 | 10.556 | 0.013 |
| C. krusei (32) | 19.027 | 20.950 | 16.812 | 0.717 |
| HSCT only | ||||
| All species (119) | 4.099 | 9.190 | 2.403 | 0.001 |
| C. albicans (23) | 0.224 | 0.250 | 0.220 | 0.383 |
| C. glabrata (41) | 23.209 | 29.748 | 18.730 | 0.219 |
| C. krusei (18) | 21.773 | 16.876 | 42.224 | 0.104 |
| SOT only | ||||
| All species (264) | 1.206 | 4.876 | 1.020 | <0.001 |
| C. albicans (131) | 0.324 | 0.372 | 0.322 | 0.537 |
| C. glabrata (78) | 9.007 | 11.016 | 8.640 | 0.513 |
| C. krusei (14) | 16.000 | 36.758 | 10.079 | 0.110 |