Table 3.
Relative Protein Levels and Oscillation Periods in MDMX-Null Cells
Mean | Standard error | CV | |
---|---|---|---|
p53 peak amplitude | 2.70 | 0.25 | 0.09 |
p53 trough amplitude | 1.62 | 0.17 | 0.10 |
p53 peak width | 6.71(h) | 0.75(h) | 0.11 |
p53 period | 6.89(h) | 0.49(h) | 0.07 |
MDM2 peak amplitude | 7.01 | 1.49 | 0.21 |
MDM2 trough amplitude | 1.64 | 0.38 | 0.23 |
MDM2 peak width | 6.69(h) | 0.82(h) | 0.12 |
MDM2 period | 6.88(h) | 0.52(h) | 0.08 |
Levels of p53 and MDM2 are normalized by the levels in cells with MDMX, 104 (p53) and 5.6 × 104 (MDM2) molecules per cell (Wang et al., 2007).