Table 2.
| |||||
---|---|---|---|---|---|
entry | X | R | product | yield (%)a | Z/Eb |
1 | CH2 | Ph | 2b | 70 | 88:12 |
2 | C(CO2Me)2 | Ph | 2c | 76 | >95:5 |
3 | NBn | Ph | 2d | 74 | 88:12 |
4 | O | n-C5H11 | 2e | 75 | >95:5 |
5 | O | CO2Me | 2f | <5c | --- |
6 | O | H | 2g | 55d | --- |
Isolated yield of the mixture of olefin isomers.
Determined by 1H NMR spectroscopy of the crude reaction mixture.
Determined by 1H NMR spectroscopy relative to mesitylene as an internal standard.
Dropwise addition of substrate via syringe pump.