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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Immunity. 2010 May 20;32(5):605–615. doi: 10.1016/j.immuni.2010.05.003

Figure 2. Loss of STAT3 Abrogates Th17 but not Th1 Cell Responses.

Figure 2

(A–C) Rag2−/− mice were injected with naive T cells from control (Stat3fl/fl) or Stat3−/− (Cd4 Cre; Stat3fl/fl) mice.

(A) IL-17A production by CD4+ T cells in the colon LP, MLNs, and spleen was measured.

(B) The overall proportion of IL-17A+ T cells represents data pooled from two independent experiments.

(C) The proportions of IFN-γ+ CD4+ T cells in the tissues of Rag2−/− mice were enumerated and pooled from two independent experiments. See also Figure S1. *p < 0.05, ***p < 0.0001.