Table I. Checkerboard analysis of IL-24 induced monocyte migration.

Human monocytes were pretreated with media (0), 1.2 ng/ml, 0.12 ng/ml or 0.001 ng/ml of IL-24 for 30 minutes prior to being placed in a micro Boyden chemotaxis chamber. Across the top of the table are the pretreatment conditions and along the left hand side of the table are the lower well chemoattractant concentrations. Reported in this table are the mean cell number and SEM for each of the conditions. N>3

The mean cell no. per high powered field ± sem from 3 donors is reported

Upper wells pretreatment/lower wells	1.2 ng/ml	0.12 ng/ml	0.001 ng/ml	0
0 ng/ml	5.9 ± 1.0#	7.0 ± 1.0	10.18 ± 1.5	8.8 ± 1.1
.001	7.7 ± 1.0	15.4 ± 1.6**	7.3 ± 0.7	6.7 ± 1.2
.12	12.6 ± 1.8*	18.4 ± 2.6**	20.9 ± 3.9**	18.4 ± 3.0**
1.2	10.4 ± 1.9	10.4 ± 2.2	n.d.	12.4 ± 2.1

^#p=0.01 reduced

^*p=0.05 increased

^**P•0.006 increased

n.d = not determined for all donors