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. Author manuscript; available in PMC: 2012 Aug 1.
Published in final edited form as: Mol Pharm. 2011 Jul 8;8(4):1390–1400. doi: 10.1021/mp200219e

Table 1.

Relaxivities and Octanol-Water Partition Coefficients

r1 (mM-1s-1) r2 (mM-1s-1) LogP
ProGlo 4.73a, 5.35 ± 0.74b 6.14 ± 0.81b 1.40 ± 0.08
Gd-Hexyl-DO3A 5.55 ± 0.22c 6.38 ± 0.38c -1.21 ± 0.12
Gd-DO3A 4.05 ± 0.02c 4.75 ± 0.35c -2.96 ± 0.35
21-Hydroxyprogesterone --- --- 2.88d
a

Measured at 4.7 T (200 MHz), 21 °C33

b

Measured in 1% DMSO in water, 1.41 T (60 MHz), 37 °C

c

Measured in water, 1.41 T (60 MHz), 37 °C

d

Measured by shake flask method/mass38