Fig. 3. Loss of Th17 cells and up-regulation of CCR6 on Th17 cells during the course of infection in the vaccinated macaques.
(A) Successive decline in the total population of Th17 cells (pre vs wk 4 and pre vs chronic, p = 0.027 for both) in vaccinated, protected macaques. (B) Up-regulation of CCR6 during the course of SHIV89.6P infection. Significantly higher expression was seen in the total Th17 population (pre vs wk4 and pre vs chronic, p = 0.0003 for both). Plotted are mean values with sem.