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(A) Increased colony formation in IGFBP-3KO:Myc cells p<0.01 by T-Test. (B) Increased invasiveness of IGFBP-3KO:Myc cells. p<0.01 by T-Test. (C) Addition of recombinant human IGFBP-3 to IGFBP-3KO:Myc cell line reverses invasive phenotype. **p<0.05 by T-test.
