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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Biochem Pharmacol. 2011 Jun 13;82(5):514–523. doi: 10.1016/j.bcp.2011.06.011

Figure 5.

Figure 5

Loss of ahr in endothelium attenuates the contribution of Ang II to basal blood pressure. (A) MAP response, (B) change in diastolic, and (C) change in systolic blood pressure, following treatment with 4 mg/kg ACEi, captopril, in drinking water for 5 d, followed by a 4 d washout. (D) Area under the curve analysis of systolic and diastolic blood pressure response during washout. Data represent mean ± SEM and were analyzed by repeated measures two-way ANOVA, using post hoc Holm-Sidak comparisons; *p < 0.05, compared to ECahr+/+ (Fig. A, B and C). Data in panel (D) were analyzed by student’s t-test *p < 0.05, compared to ECahr+/+ (n=4/genotype).