Table 2.
Comparison of co-morbidities and prescription medications between the SLE patients and the non-SLE controls.
| SLE Patients(n = 10337) | Non-SLE Patients(n = 62022) | p-value | |
| Variables | |||
| Co-morbid medical conditions | |||
| Diabetes | 218 (2.1) | 1565 (2.5) | 0.012 |
| Lymphoma | 22 (0.2) | 18 (0.0) | <0.001 |
| Leukemia | 9 (0.1) | 10 (0.0) | <0.001 |
| Breast cancer | 17 (0.2) | 154 (0.3) | 0.104 |
| Liver cancer | 11 (0.1) | 18 (0.0) | <0.001 |
| HIV/AIDS | 0 (0.0) | 2 (0.0) | 0.564 |
| Charlson co-morbidity index, mean ± SD | 7.83 ± 1.22 | 0.23 ± 0.81 | <0.001 |
| Prescription medication | |||
| Systemic corticosteroid | 9695 (93.8) | 30254 (48.8) | <0.001 |
| Prednisolone equivalent dose (mg/day) | <0.001 | ||
| No use | 648 (6.3) | 32046 (51.7) | |
| 0-10 | 6588 (63.7) | 29946 (48.3) | |
| 10-20 | 2300 (22.3) | 26 (0.0) | |
| >20 | 801 (7.7) | 4 (0.0) | |
| Azathioprine | 3661 (35.4) | 29 (0.0) | <0.001 |
| Cyclophosphamide | 2287 (22.1) | 106 (0.2) | <0.001 |
| Methotrexate | 859 (8.3) | 140 (0.2) | <0.001 |
| Cyclosporin | 250 (2.4) | 28 (0.0) | <0.001 |
| Hydroxychloroquine | 8179 (79.1) | 199 (0.3) | <0.001 |
Values are the number of patients (percentage), unless otherwise indicated.