Table 6.
Time of action | Concentration | D3 | D4 | D5 | D6 | |||||
---|---|---|---|---|---|---|---|---|---|---|
Before and during (a) | BT | 75 μg/mL | (+) | (+) | ++ | ++ | T | T | T | T |
AZT | 0.4 μM | (+) | (+) | + | + | T | T | T | T | |
During (b) | BT | 75 μg/mL | (+) | + | +/++ | +/++ | T | T | T | T |
AZT | 0.4 μM | (+) | (+) | +/++ | +/++ | T | T | T | T | |
After (c) | BT | 75 μg/mL | - | - | - | - | - | - | - | - |
AZT | 0.4 μM | - | - | - | - | - | - | - | - | |
All the time (d) | BT | 75 μg/mL | - | - | - | - | - | + | - | + |
AZT | 0.4 μM | - | - | - | - | - | - | - | - | |
Control HIV-1 NDK 1 × 10−4 | ++ | ++ | ++ | ++/++T | T | T | T | T | ||
++ | + | ++ | ++ | T | T | T | T | |||
Before and during (a) | BT | 75 μg/mL | + | (+)/+ | ++ | ++ | ++T | T | T | T |
AZT | 0.4 μg/mL | (+) | - | + | (+)/+ | ++T | ++T | T | T | |
During (b) | BT | 75 μg/mL | + | + | ++ | ++ | T | T | T | T |
AZT | 0.4 μg/mL | (+) | (+) | + | +/++ | T | ++T | T | T | |
After (c) | BT | 75 μg/mL | - | - | - | - | - | - | - | - |
AZT | 0.4 μg/mL | - | - | - | - | - | - | - | - | |
All the time (d) | BT | 75 μg/mL | (+) | - | - | + | - | + | - | + |
AZT | 0.4 μg/mL | - | - | - | - | - | - | - | - | |
Control HIV-1 NDK 7.5 × 10−5 | + | + | + | + | T | T | T | T | ||
++ | ++ | + | +/++ | T | T | T | T | |||
MT4 | - | - | - | - | - | - | - | - |
-: absence of syncitium in all the well; (+): presence of 1 or 2 syncitium by field; + and ++: presence of many syncitium per field; T: cellular death due to the viral replication; D: days.