Table 1.
Patient characteristics by self-reported hypoglycemic symptoms
| Characteristic | All Patients | With Hypoglycemic Symptoms | Without Hypoglycemic Symptoms | p-value |
|---|---|---|---|---|
| N = 1984 | n = 1248 (63%) | n = 736 (37%) | ||
| Female (%) | 43 | 47 | 37 | <.0001§ |
| Male (%) | 57 | 53 | 63 | |
| Age, years | 58.1 ± 11.1 | 56.8 ± 11.2 | 60.4 ± 10.4 | <.0001‡ |
| Body mass index, kg/m2 | 34.5 ± 8.2 | 34.8 ± 8.4 | 34.0 ± 7.9 | 0.0229‡ |
| Duration of diabetes, years | 7.3 ± 6.4* | 7.2 ± 6.2 | 7.5 ± 6.6 | 0.2737‡ |
| HbA1c <7%† (%) | 72.2 | 71.4 | 73.6 | 0.3667§ |
| Any weight gain (%) | 36.9 | 41.5 | 29.1 | <.0001§ |
| Amount of weight gain | ||||
| <10 lbs (%) | 27.9 | 25.9 | 32.7 | |
| 10-20 lbs (%) | 47.5 | 48.7 | 44.9 | <.0001¶ |
| 21-30 lbs (%) | 12.3 | 12.6 | 11.7 | |
| >30 lbs (%) | 12.3 | 12.9 | 10.8 | |
| Microvascular (%) | 22.5 | 25.8 | 16.9 | <.0001§ |
| Macular edema (%) | 4.0 | 4.8 | 2.6 | 0.0143§ |
| Kidney disease (%) | 2.5 | 2.9 | 1.8 | 0.1210§ |
| Foot or leg ulcer (%) | 3.6 | 4.2 | 2.6 | 0.0663§ |
| Neuropathic pain (%) | 17.3 | 20.4 | 12.1 | <.0001§ |
| Selected cardiovascular conditions (%) | 19.5 | 21.6 | 15.9 | 0.0018§ |
| Angina (%) | 8.5 | 9.9 | 6.3 | 0.0054§ |
| Heart attack (%) | 8.0 | 8.2 | 7.7 | 0.7342§ |
| Stroke (%) | 4.3 | 4.7 | 3.5 | 0.2042§ |
| Peripheral vascular disease (%) | 0.96 | 1.0 | 0.82 | 0.6169§ |
| Congestive heart failure (%) | 4.3 | 4.7 | 3.7 | 0.2983§ |
| Current antihyperglycemic agents regimen | ||||
| Treatment regimen including a sulfonylurea (%) | 50 | 55 | 42 | <.0001¶ |
| All other treatment regimens (%) | 50 | 45 | 58 | |
Data are presented as frequency and mean ± standard deviation.
*median 6 yrs.; 25th percentile 3 yrs.; 75th percentile 10 yrs.
†n = 1439
Based on ‡ t-test, § chi-square, or ¶ Wald test of joint significance.