Table 1.

Synonymous codon usage in Cardiovirus genome

AAa	Codon	bRSCU	Codon	bRSCU
	EMCV		ThV
Ala	GCU(A)	1.21	GCU(A)	1.64
	GCC(A)	1.45	GCC(A)	1.05
	GCA(A)	0.80	GCA(A)	1.02
	GCG(A)	0.54	GCG(A)	0.29
Arg	CGU(R)	0.91	CGU(R)	0.82
	CGC(R)	0.74	CGC(R)	0.94
	CGA(R)	0.28	CGA(R)	0.50
	CGG(R)	0.61	CGG(R)	0.32
	AGA(R)	2.60	AGA(R)	2.67
	AGG(R)	0.87	AGG(R)	0.75
Asn	AAU(N)	1.17	AAU(N)	1.07
	AAC(N)	0.83	AAC(N)	0.93
Asp	GAU(D)	1.17	GAU(D)	0.98
	GAC(D)	0.83	GAC(D)	1.02
Cys	UGU(C)	0.97	UGU(C)	1.23
	UGC(C)	1.04	UGC(C)	0.77
Gln	CAA(Q)	0.83	CAA(Q)	1.26
	CAG(Q)	1.17	CAG(Q)	0.74
Glu	GAA(E)	0.93	GAA(E)	1.38
	GAG(E)	1.07	GAG(E)	0.62
Gly	GGU(G)	1.06	GGU(G)	1.14
	GGC(G)	0.92	GGC(G)	1.01
	GGA(G)	1.25	GGA(G)	1.53
	GGG(G)	0.77	GGG(G)	0.32
His	CAU(H)	1.23	CAU(H)	0.84
	CAC(H)	0.77	CAC(H)	1.16
Ile	AUU(I)	1.61	AUU(I)	1.55
	AUC(I)	0.66	AUC(I)	0.85
	AUA(I)	0.73	AUA(I)	0.60
Leu	UUA(L)	0.43	UUA(L)	0.73
	UUG(L)	1.40	UUG(L)	1.40
	CUU(L)	0.95	CUU(L)	1.35
	CUC(L)	1.03	CUC(L)	1.25
	CUA(L)	0.78	CUA(L)	0.49
	CUG(L)	1.41	CUG(L)	0.77
Lys	AAA(K)	0.83	AAA(K)	1.15
	AAG(K)	1.17	AAG(K)	0.85
Phe	UUU(F)	1.10	UUU(F)	1.08
	UUC(F)	0.90	UUC(F)	0.92
Pro	CCU(P)	1.04	CCU(P)	1.42
	CCC(P)	1.12	CCC(P)	1.16
	CCA(P)	1.37	CCA(P)	1.02
	CCG(P)	0.47	CCG(P)	0.40
Ser	AGU(S)	0.60	AGU(S)	0.53
	AGC(S)	0.52	AGC(S)	0.45
	UCU(S)	1.57	UCU(S)	1.82
	UCC(S)	1.36	UCC(S)	1.44
	UCA(S)	1.40	UCA(S)	1.37
	UCG(S)	0.55	UCG(S)	0.39
Thr	ACU(T)	1.27	ACU(T)	1.49
	ACC(T)	1.31	ACC(T)	1.21
	ACA(T)	1.13	ACA(T)	1.05
	ACG(T)	0.29	ACG(T)	0.25
Tyr	UAU(Y)	0.99	UAU(Y)	0.94
	UAC(Y)	1.01	UAC(Y)	1.06
Val	GUU(V)	0.90	GUU(V)	1.53
	GUC(V)	0.96	GUC(V)	0.94
	GUA(V)	0.66	GUA(V)	0.62
	GUG(V)	1.48	GUG(V)	0.91

a Amino acid

b The RSCU value is a mean value of each codon for a particular

amino acid